TMPRSS4 Protein (AA 1-435) (His tag)

Catalog No. ABIN7559807

Product Details

Target: TMPRSS4 (Transmembrane Protease, serine 4 (TMPRSS4))

Protein Type: Recombinant

Protein Characteristics: AA 1-435

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This TMPRSS4 protein is labelled with His tag.

Purpose: Made-to-order recombinant Tmprss4 Protein expressed in mammalian cells.

Sequence: MESDSGQPLN NRDIVPFRKP RRPQETFKKV GIPIIAVLLS LIALVIVALL IKVILDKYYF ICGSPLTFIQ RGQLCDGHLD CASGEDEEHC VKDFPEKPGV AVRLSKDRST LQVLDAATGT WASVCFDNFT EALAKTACRQ MGYDSQPAFR AVEIRPDQNL PVAQVTGNSQ ELQVQNGSRS CLSGSLVSLR CLDCGKSLKT PRVVGGVEAP VDSWPWQVSI QYNKQHVCGG SILDPHWILT AAHCFRKYLD VSSWKVRAGS NILGNSPSLP VAKIFIAEPN PLYPKEKDIA LVKLQMPLTF SGSVRPICLP FSDEVLVPAT PVWVIGWGFT EENGGKMSDM LLQASVQVID STRCNAEDAY EGEVTAEMLC AGTPQGGKDT CQGDSGGPLM YHSDKWQVVG IVSWGHGCGG PSTPGVYTKV TAYLNWIYNV RKSEM Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TMPRSS4 (Transmembrane Protease, serine 4 (TMPRSS4))

Alternative Name: Tmprss4 (TMPRSS4 Products)

Background: Transmembrane protease serine 4 (EC 3.4.21.-) (Channel-activating protease 4) (mCAP2) [Cleaved into: Transmembrane protease serine 4 catalytic chain],FUNCTION: Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity (By similarity). Seems to be capable of activating ENaC (PubMed:12149280). {ECO:0000250|UniProtKB:Q9NRS4, ECO:0000269|PubMed:12149280}.

Molecular Weight: 47.5 kDa

UniProt: Q8VCA5

AlphaFold: Q8VCA5