SLC44A4 Protein (AA 1-707) (His tag)

Catalog No. ABIN7559980

This Recombinant SLC44A4 protein is produced in HEK-293 Cells.

Quick Overview for SLC44A4 Protein (AA 1-707) (His tag) (ABIN7559980)

Target: SLC44A4 (Solute Carrier Family 44, Member 4 (SLC44A4))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-707

Purification tag / Conjugate: This SLC44A4 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Slc44a4 Protein expressed in mammalian cells.

Sequence: MGRKQNENEA HGNSAKYDPS FRGPIKNRGC TDIICCVLFL IFILGYIIVG LVAWVYGDPR QVLYPRNSTG AYCGVGDNKD KPYVLYFDIL SCAAAINIIS IAENGLQCPT PQVCVSSCPL APWAVEVFQF SKTVGEVYGE RRNFCLPAVS PDMIVEESLQ KGLCPRFLLP STPALGRCFP LPNINFTLPE DLRINNTTVS NGISGLLDSI NARDVSVKIF EDFAQSWYWI LVALGVALAL SLLFILLLRL VAAPLVLLLI VGVLAVLAYG IYHCWQQYQV FRDKGASITQ LGFTTNFSAY QSVKETWLAA LIVLAVLEGI LLLMLIFLRQ RIRIAIALLK EASRAVGQMM STMFYPLVTF VLLVICIGYW AVTALYLATS GQPQYIYWAS NTSTPGCENV PVNMTCDPMA PLNSSCPNLK CVFKGYSTTG LAQRSLFNLQ IYGVLGLFWT VNWVLALGQC VLAGAFASFY WAFHKPRDIP TFPLSSAFIR TLRYHTGSLA FGALILSLVQ IARVILEYID HKLRGSQNPV ARCIICCFKC CLWCLEKFIK FLNRNAYIMI AIYGKNFCVS AKNAFMLLMR NVLRVVVLDK VTDLLLFFGK LLVVGGVGVL SFFFFSGRIK GLGKDFENPN LNYYWLPIMT SIMGAYVIAS GFFSVFGMCV DTLFLCFLED LERNDGSQER PYYMPKALLK ILGKKNEAPT GGKTRKK Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SLC44A4 (Solute Carrier Family 44, Member 4 (SLC44A4))

Alternative Name: Slc44a4

Background: Choline transporter-like protein 4 (Solute carrier family 44 member 4) (Thiamine pyrophosphate transporter 1) (mTPPT1),FUNCTION: Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (PubMed:24379411). {ECO:0000250|UniProtKB:Q53GD3, ECO:0000250|UniProtKB:Q7T2B0, ECO:0000269|PubMed:24379411}.

Molecular Weight: 78.7 kDa

UniProt: Q91VA1

AlphaFold: Q91VA1