RABEP2 Protein (AA 1-554) (His tag)

Catalog No. ABIN7560037

This Recombinant RABEP2 protein is produced in HEK-293 Cells.

Quick Overview for RABEP2 Protein (AA 1-554) (His tag) (ABIN7560037)

Target: RABEP2 (Rabaptin, RAB GTPase Binding Effector Protein 2 (RABEP2))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-554

Purification tag / Conjugate: This RABEP2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Rabep2 Protein expressed in mammalian cells.

Sequence: MAAAPATLAL DPQPQEKQKD ASESSELSRL RAELAGALAE METMKAVAEV SESTKAEAVA AVQRQCQEEV ASLQAILKDS ISSYETQIAA LKQERQQQQQ DFEEKDRELG HLKQLLARAH PLDSLEKQME KAHEDSEKLR EIVLPMEQEI TELKGKLQRA EELIQEIQRR PRQPASLHGS TELLPLSRNP SPPLEPLEEP SGDAGPAAEA FAHNCDDSAS ISSFSLGGAA GSASLRGPQG LSPEQEETAS LVSTGTLVPE GIFLPPPGYQ LVPDSQWEQL QVEGRQLQKE LESVSRERDE LQEGLRRSNE DCAKQMQVLL AQVQNSEQLL RTLQGTVSQA QERVQLQMAE LATSHKCLSQ EVKRLNEENQ GLRAEQLPSS ALQGSEQRED QDEALPSSIQ ELHLLVQNTR QQARARQQAQ EHEAERLRIE IVKLREALDE ETAAKASLER QLRVQREETD VLEASLCSLR IETERVQQEQ RKAQLTDLLS EQRAKTLRLQ AELETSEQVQ RDFVRLSQAL QVRLERIRQA ETLQQVRSIL DEAPLRDIRD IKDS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: RABEP2 (Rabaptin, RAB GTPase Binding Effector Protein 2 (RABEP2))

Alternative Name: Rabep2

Background: Rab GTPase-binding effector protein 2 (Rabaptin-5beta),FUNCTION: Plays a role in membrane trafficking and in homotypic early endosome fusion. Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking. By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis. {ECO:0000250|UniProtKB:Q9H5N1}.

Molecular Weight: 62.1 kDa

UniProt: Q91WG2

AlphaFold: Q91WG2