TH1-Like Protein (TH1L) (AA 1-591) (His tag)
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- Target See all TH1-Like (TH1L) Proteins
- TH1-Like (TH1L)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-591
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TH1-Like protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Nelfcd Protein expressed in mammalian cells.
- Sequence
- MAGPAPGTIM GEDYFGNASE WGEEADGGQH QEDDSGEGED DAEVQQECLH KFSTRDYIME PSIFNTLKRY FQAGGSPENV IQLLSENYTA VAQTVNLLAE WLIQTGVEPV QVQETVENHL KSLLIKHFDP RKADSIFTEE GETPAWLEQM IAHTTWRDLF YKLAEAHPDC LMLNFTVKLI SDAGYQGEIT SVSTACQQLE VFSRVLRTSL ATILDGGEEN LEKNLPEFAK MVCHGEHTYL FAQAMMSVLA QEEQGGSAVR RVAQEVQRFA QEKGHDASQI TLALGTAASY PRACQALGAM LSRGALNPAD ITVLFKMFTS MDPPPVELIR VPAFLDLFMQ SLFKPGAKIN QDHKHKYIHI LAYAASVVET WKKNKRVSIG KDELKSTSKA IETVHNLCCN ENKGASELVA ELSTLYQCIR FPVVAMGVLK WVDWTVSEPR YFQLQTDHTP VHLALLDEIS TCHQLLHPQV LQLLVKLFET EHSQLDVMEQ LELKKTLLDR MVHLLSRGYV LPVVSYIRKC LEKLDTDISL IRYFVTEVLD VIAPPYTSDF VQLFLPILEN DSIAGTIKAE GEHDPVTEFI AHCKSNFIVV N Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product TH1L Protein
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TH1-Like (TH1L) (AA 1-590) protein (His tag)
custom-made TH1L Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TH1-Like (TH1L) (AA 1-590) protein (GST tag)TH1L Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
TH1-Like (TH1L) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TH1L Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- TH1-Like (TH1L)
- Alternative Name
- Nelfcd (TH1L Products)
- Background
- Negative elongation factor D (NELF-D) (TH1-like protein),FUNCTION: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity). The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity). {ECO:0000250|UniProtKB:Q8IXH7}.
- Molecular Weight
- 66.3 kDa
- UniProt
- Q922L6
- AlphaFold
- Q922L6
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