OCSTAMP Protein (AA 1-498) (His tag)

Catalog No. ABIN7561030

Product Details

Target: OCSTAMP (Osteoclast Stimulatory Transmembrane Protein (OCSTAMP))

Protein Type: Recombinant

Protein Characteristics: AA 1-498

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This OCSTAMP protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Ocstamp Protein expressed in mammalian cells.

Sequence: MRTIRAATEH LFGLGWKFWR LGICKAVVPL QAAWKAFSQP VPASCNELLT QLLLCVSLAS LIAGLAHHWL VSLQLYPLGP PALVTSLCGL FVFLSLGLVP PIRCLFVLSV PTLGSKQGRR LLLSYSAANL AVAVVPNVLG NVRAAGQVLS CVTEGSLESL LNTTYQLRQA ARELGPASRA GSRSLTFEVE GKGSAFRLHM HTITQEILED FSGLEFLARA ALGTQRVVTG LFLLGLLGES AWYLHRYLTD LRFDNIYATR QLVRQLAQAG ATHLLTSPPP WLLQTAQPKL SREELLSCLL RLGLLALLLV ATAVTVASDY GAFLLAQAAV AWAQKLPTVP ITLTVKYDAS YKVLDFILFV LNQPPVESVF ASMQRSFQWE LRFTPHDCHL PQAQPPRVTA ALAAGALQLL AGATLVLQAY AWRLRHTIAA SFFPDQEARR LSHLQARLQR RHNQSDHLNK QPGTMATRES RKPGQGTRTL ESQGPQAHDS LGPPYDLE Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: OCSTAMP (Osteoclast Stimulatory Transmembrane Protein (OCSTAMP))

Alternative Name: Ocstamp (OCSTAMP Products)

Background: Osteoclast stimulatory transmembrane protein (OC-STAMP),FUNCTION: Probable cell surface receptor that plays a role in cellular fusion and cell differentiation. Cooperates with DCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Involved in osteoclast bone resorption. Promotes osteoclast differentiation and may play a role in the multinucleated osteoclast maturation. {ECO:0000269|PubMed:18064667, ECO:0000269|PubMed:20882308, ECO:0000269|PubMed:22337159}.

Molecular Weight: 54.6 kDa

UniProt: Q9D611

AlphaFold: Q9D611