Parvin, beta Protein (PARVB) (AA 1-365) (His tag)
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- Target See all Parvin, beta (PARVB) Proteins
- Parvin, beta (PARVB)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-365
- Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Parvin, beta protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Parvb Protein expressed in mammalian cells.
- Sequence
- MSSAPPRSPT PRAPKMKKDE SFLGKLGGTL ARKKKTREVT DLQEEGKSAI NSPMAPALVD IHPEDTQLEE NEERTMIDPT SREDPKFKEL VKVLLDWIND VLAEERIIVK QLEEDLYDGQ VLQKLLEKLA HCKLNVAEVT QSEIGQKQKL QTVLEAVQDL LRPHGWPLRW NVDSIHGKNL VAILHLLVSL AMHFRAPIHL PEHVTVQVVV VRKREGLLHS SHISEELTTT TEIMMGRFER DAFDTLFDHA PDKLNLVKKS LITFVNKHLN KLNLEVTDLE TQFADGVYLV LLLGLLEDYF VPLHNFYLTP DSFDQKVHNV AFAFELMLDG GLKKPKARPE DVVNLDLKST LRVLYTLFTK YKDVE Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Parvin, beta (PARVB) (AA 1-364) protein (His tag)
custom-made PARVB Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Parvin, beta (PARVB) (AA 1-350) protein (GST tag)PARVB Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Parvin, beta (PARVB) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PARVB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- Parvin, beta (PARVB)
- Alternative Name
- Parvb (PARVB Products)
- Background
- Beta-parvin,FUNCTION: Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration (By similarity). {ECO:0000250}.
- Molecular Weight
- 41.7 kDa
- UniProt
- Q9ES46
- AlphaFold
- Q9ES46
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