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IRX5 Protein (AA 1-484) (His tag)

custom-made IRX5 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7561644
  • Target See all IRX5 Proteins
    IRX5 (Iroquois Homeobox Protein 5 (IRX5))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-484
    Origin
    • 3
    • 1
    • 1
    • 1
    Mouse
    Source
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IRX5 protein is labelled with His tag.
    Purpose
    Predefined custom protein recombinant Irx5 Protein expressed in mammalian cells.
    Sequence
    MSYPQGYLYQ PSASLALYSC PAYSTSVISG PRTDELGRSS SGSAFSPYAG STAFTAPSPG YNSHLQYGAD PAAAAAAAFS YVGSPYDHTP GMAGSLGYHP YAAPLGSYPY GDPAYRKNAT RDATATLKAW LNEHRKNPYP TKGEKIMLAI ITKMTLTQVS TWFANARRRL KKENKMTWTP RNRSEDEEEE ENIDLEKNDE DEPQKPEDKG DLEGPESGGA EQKATAGCER LQGPLSPAGK ETEGSLSDSD FKESSSEGRH DELPRPPRAG ESSPAGPATA RLAEDAGPHY PASVPAPGPH PSAGELPPGS GGSSVIHSPP PPPPPPPAVL AKPKLWSLAE IATSSDKVKD GGGGSEGSPC PPCPGPMGGQ TLGGSRASPA PAPARSPSAQ CPFPGGTVLS RPLYYTAPFY PGYTNYGSFG HLHGHPGPGP SPTAGPGSHF NGLNQTVLNR ADVLAKDPKM LRSQSQLDLC KDSPYELKKG MSDI Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
    Specificity
    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
    Characteristics
    Key Benefits:
    • Predefined custom protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
    Purity
    > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
    Grade
    custom-made
    Top Product
    Discover our top product IRX5 Protein
  • Application Notes
    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    The buffer composition is at the discretion of the manufacturer.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C.
    Expiry Date
    12 months
  • Target
    IRX5 (Iroquois Homeobox Protein 5 (IRX5))
    Alternative Name
    Irx5 (IRX5 Products)
    Background
    Iroquois-class homeodomain protein IRX-5 (Homeodomain protein IRXB2) (Iroquois homeobox protein 5),FUNCTION: Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina. Involved in craniofacial and gonadal development (By similarity). Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12. {ECO:0000250}.
    Molecular Weight
    50.8 kDa
    UniProt
    Q9JKQ4
    AlphaFold
    Q9JKQ4
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