GIT2 Protein (AA 1-708) (His tag)

Catalog No. ABIN7561681

This Recombinant GIT2 protein is produced in HEK-293 Cells.

Quick Overview for GIT2 Protein (AA 1-708) (His tag) (ABIN7561681)

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-708

Purification tag / Conjugate: This GIT2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Git2 Protein expressed in mammalian cells.

Sequence: MSKRLRSSDV CADCNGPDPS WASVNRGTFI CDECCSVHRS LGRHISQVRH LKHTAWPPTL LQMVETLYNN GANSIWEHSL LDPASIMSGR RKANPQDKVH PNKAEFIRAK YQMLAFVHRL PCREDDSVTA KDLSKQLHSS VRTGNLETCL RLLSLGAQAN FFHPEKGSTP LHVASKAGQI LQAELLAVYG ADPGTQDSSG KTPVDYARQG GHHELAERLI EIQYELTDRL AFYLCGRKPD HKSGQHFLIP QRADSLDLSE LAKAAKKKLQ SLSNHLFEEL AMDVYDEVDR RETDAVWLAT QNHSTLVTET TVVPFLPVNP EYSSTRNQGR QKLARFNAHE FATLVIDILS DAKRRQQGSP LSRSKDNVEL ILRTVSTQHS TESQDNDQPD YDSVASDEDT DVETRASKAN RQKLQTLQSE NSSLRRQATA SACQVQTGSD HKDTASHSSL KRRPSARGSR PMSMYETGSG QKPYLPMGEA SHPEESRTRL QPFPTHIGRS ALVTSSSSLP SFPSTLSWSR DESARRASRL EKQNSTPESD YDNTACDPEP DDTGSTRKGR QRSMLWQGDG LLPDTAEPHS VPSPTLPSTE DVIRKTEQIT KNIQELLRAA QENKHDSYIP CSERIHVAVT EMAALFPKKP KSDTVRTSLR LLTSSAYRLQ SECRKALPGD SSLPTDVQLV TQQVIQCAYD IAKAAKQLVT ITTKENSS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Alternative Name: Git2

Background: ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2),FUNCTION: GTPase-activating protein for ADP ribosylation factor family members, including ARF1. {ECO:0000250|UniProtKB:Q14161}.

Molecular Weight: 78.8 kDa

UniProt: Q9JLQ2

AlphaFold: Q9JLQ2

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling