AZI2 Protein (AA 1-405) (His tag)
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- Target See all AZI2 Proteins
- AZI2 (5-Azacytidine Induced 2 (AZI2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-405
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This AZI2 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Azi2 Protein expressed in mammalian cells.
- Sequence
- MDTLVEDDIC ILNHEKAHRR EAVTPLSAYP GDESVASHFA LVTAYEDIKK RLKDSEKENS FLKKRIRALE ERLVGARADE ETSSVGREQV NKAYHAYREV CIDRDNLKNQ LEKINKDNSE SLKMLNEQLQ SKEVELLQLR TEVETQQVMR NLNPPSSSWE VEKLSCDLKI HGLEQELGLL RKECSDLRTE LQKARQTGPP QEDILQGRDV IRPSLSREEH VPHQGLHHSD NMQHAYWELK REMSNLHLVT QVQAELLRKL KTSAAVKKAC TPVGCVEDLG RDSTKLHLTN FTATYKRHPS LSPNGKAPCY APSSPLPGDR KVFSDKAVLQ SWTDNERLVP NDGADFPEHS SYGRNSLEDN SWVFPSPPKS SETAFGENKS KILPLSNLPP LHYLDQQNQN CLYKS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product AZI2 Protein
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5-Azacytidine Induced 2 (AZI2) (AA 1-392) protein (His tag)
custom-made AZI2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
5-Azacytidine Induced 2 (AZI2) (AA 1-392) protein (GST tag)AZI2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
5-Azacytidine Induced 2 (AZI2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)AZI2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- AZI2 (5-Azacytidine Induced 2 (AZI2))
- Alternative Name
- Azi2 (AZI2 Products)
- Background
- 5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (Nap1),FUNCTION: Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1. {ECO:0000269|PubMed:17568778, ECO:0000269|PubMed:22539786}.
- Molecular Weight
- 46.1 kDa
- UniProt
- Q9QYP6
- AlphaFold
- Q9QYP6
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