HERC6 Protein (AA 1-1003) (His tag)

Catalog No. ABIN7562141

This Recombinant HERC6 protein is expressed in HEK-293 Cells.

Quick Overview for HERC6 Protein (AA 1-1003) (His tag) (ABIN7562141)

Target: HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1003

Purification tag / Conjugate: This HERC6 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Herc6 Protein expressed in mammalian cells.

Sequence: MYFSWAAGSR KPRRLKAGTS GIELLQAASG EHHSLLLFSN HRVYSCGDNS WGQLGQRRDQ STERPEPIQA LNDLHVDLVS CGKEHSVAVC HKGKVFAWGA GSEGQLGIGE FKEISFMPTK IKALAGIKII QVSCGHYHSL ALSEDGHVFS WGRNSEGQLG LGKNSRSQAI PQKVKSLEGI PLAQVAAGGT HSFALSLTGT SFGWGSNRSG QLALSGNKVK EQIYKPHSIG ALKNLSVIYI SCGYEHTAVL TEEGQVFTFG GNSSGQLQPS PRSGQRGPQL IEGIGGRVSQ IECASYHTIA YVYTTGQVVS LGRGPSHTSN PTHQEAPAEN SDITCLLAAE DLVDIEVKDI FAGAHANFVT TRRVSHTRST GVSMKILPEI IRINQSLVKK WRAANKRKDR EGAKREISLI FSSSACLTAS FLKKRDAGEN NLIDVDLKLA RDVFKKLTTE KWISSLITTC LEEYLLRDLP YSSPHQEALL VFLLLPECSI MQDPKNWKTL AFEFAKAIHK MGPQSLAFLR TCWASLEVSS LNILVQMLKK AIISQIQYGV ATEQYITNIK VLLEVIKEVH KANCQLPESA FIINELSGIF NFDAEAGRMF IRHNDLDCTE SSDMVVFSDF LFVFDLPSKI KLMKCDSFVK LMSEVMAFPE KMSSPPYLIL KVRRSHLVED TLRQLRQVED FDLRKQLSVG FINEIRPEAG GVSSEFFHCI FEEMTDPKYE MFIYPEKGSS MWFPVNPKFE KSSYFLFGIL CGLSLHNLKV INLPFPLALY KKLLNQKPSL EDLKELSLPL GRNLQEVLNC EAGDIEELHM YFSIYWDQKD VDLIPDGISV PVNETNKRDY VSKYVDYIFN ISIKTIYEEF HRGFYKVCNW DIIRQFQPEE LMTAIIGNAT CDWKQFENNS KYKDGYDKSH PTILLFWKAF HDLTLDEKKK FLLFLTGCDR LHVKGLQNEG IVFRCSETFS EEDNPRSLTC HRMLDLPKYS SMRRMKEALQ VAINNSTGFV SQE Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))

Alternative Name: Herc6

Background: E3 ISG15--protein ligase Herc6 (EC 2.3.2.-),FUNCTION: Major E3 ligase for ISG15 conjugation. Acts as a positive regulator of innate antiviral response in cells induced by interferon. {ECO:0000269|PubMed:22272257}.

Molecular Weight: 112.9 kDa

UniProt: F2Z461

AlphaFold: F2Z461