PRRT1 Protein (AA 1-306) (His tag)
custom-made
PRRT1
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all PRRT1 products
- PRRT1 (Proline Rich Transmembrane Protein 1 (PRRT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-306
- Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PRRT1 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Prrt1 Protein expressed in mammalian cells.
- Sequence
- MSSEKSGLPD SVPHTSPPPY NAPQPPAEPP IPPPQTAPSS HHHHHHHYHQ SGTATLPRLG AGGLASAAAS AQRGPSSSAT LPRPPHHAPP GPAAGAPPPG CATLPRMPPD PYLQETRFEG PLPPPPPAAA APPPPAPAPT AQAPGFVVPT HAGAVGTLPL GGYVAPGYPL QLQPCTAYVP VYPVGTPYAG GTPGGPGVTS TLPPPPQGPG LALLEPRRPP HDYMPIAVLT TICCFWPTGI IAIFKAVQVR TALARGDLVS AEIASREARN FSFISLAVGI AAMVLCTILT VVIIIAAQHH ENYWDP Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Proline Rich Transmembrane Protein 1 (PRRT1) (AA 1-306) protein (His tag)
custom-made PRRT1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- PRRT1 (Proline Rich Transmembrane Protein 1 (PRRT1))
- Alternative Name
- Prrt1 (PRRT1 Products)
- Background
- Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1) (Synapse differentiation-induced protein 4) (SynDIG4),FUNCTION: Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function (PubMed:29490264). Regulates AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses (PubMed:29490264, PubMed:31216424). Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression (PubMed:31216424). {ECO:0000269|PubMed:29490264, ECO:0000269|PubMed:31216424}.
- Molecular Weight
- 31.4 kDa
- UniProt
- O35449
- AlphaFold
- O35449
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