LSM2 Protein (AA 1-95) (His tag)
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- Target See all LSM2 Proteins
- LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-95
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LSM2 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Lsm2 Protein expressed in mammalian cells.
- Sequence
- MLFYSFFKSL VGKDVVVELK NDLSICGTLH SVDQYLNIKL TDISVTDPEK YPHMLSVKNC FIRGSVVRYV QLPADEVDTQ LLQDAARKEA LQQKQ Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2) (AA 1-95) protein (His tag)
custom-made LSM2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2) (AA 1-95) protein (His tag)LSM2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))
- Alternative Name
- Lsm2 (LSM2 Products)
- Background
- U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (snRNP core Sm-like protein Sm-x5),FUNCTION: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. {ECO:0000250|UniProtKB:Q9Y333}.
- Molecular Weight
- 10.8 kDa
- UniProt
- O35900
- AlphaFold
- O35900
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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