BIM Protein (AA 1-196) (His tag)
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- Target See all BIM (BCL2L11) Proteins
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-196
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BIM protein is labelled with His tag.
- Purpose
- Custom-made recombinant Bcl2l11 Protein expressed in mammalian cells.
- Sequence
- MAKQPSDVSS ECDREGGQLQ PAERPPQLRP GAPTSLQTEP QGNPDGEGDR CPHGSPQGPL APPASPGPFA TRSPLFIFVR RSSLLSRSSS GYFSFDTDRS PAPMSCDKST QTPSPPCQAF NHYLSAMASI RQSQEEPEDL RPEIRIAQEL RRIGDEFNET YTRRVFANDY REAEDHPQMV ILQLLRFIFR LVWRRH Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product BCL2L11 Protein
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BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-198) protein (His tag)
custom-made BCL2L11 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-112) protein (GST tag)BCL2L11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-109) protein (GST tag)BCL2L11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-198), (full length) protein (His-SUMO Tag)BCL2L11 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-198), (full length) protein (His tag)BCL2L11 Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Alternative Name
- Bcl2l11 (BCL2L11 Products)
- Background
- Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death),FUNCTION: Induces apoptosis and anoikis. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent. {ECO:0000269|PubMed:9430630}.
- Molecular Weight
- 22.1 kDa
- UniProt
- O54918
- AlphaFold
- O54918
- Pathways
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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