MPP3 Protein (AA 1-568) (His tag)

Catalog No. ABIN7562690

Product Details

Target: MPP3 (Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) (MPP3))

Protein Type: Recombinant

Protein Characteristics: AA 1-568

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This MPP3 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Mpp3 Protein expressed in mammalian cells.

Sequence: MPVLSEDSGL HETLALLTSQ LRPDSNHREE MGFLRDVFSE KSLSYLMKIH EKLRYYERQS PTPVLHSAMA LAEDVMEELQ AASVHSDERE LLQLLSTPHL RAVLMVHDTV AQKNFDPVLP PLPDNIDEDF EEESVKIVRL VKNKEPLGAT IRRDEHSGAV VVARIMRGGA ADRSGLVHVG DELREVNGIA VLHKRPDEIS QILAQSQGSI TLKIIPATQE EDRFKDSKVF MRALFHYDPR EDRAIPCQEA GLPFQRRQVL EVVSQDDPTW WQAKRVGDTN LRAGLIPSKQ FQERRLSYRR TTGTLPSPQN FKKPPYDQPC DKETCDCDGY FKGHYVAGLR RSFRLGCRER LGGSQEAKVP TGAESQVLLT YEEVARYQHQ PGERPRLVVL IGSLGAHLHE LKQRVVAEDP QQFAVAVPHT TRPRKSHERD GVEYHFVSKQ AFEADVHHNK FLEHGEYKEN LYGTSLEAIQ AVMAKNKVCL VDVEPEALRH LRTPEFKPYV IFVKPAIQER RKTPPVSPDS EDIASSLDEQ QQEMAASAAF IDQHYGHLID TVLVRQDLQE PAASSELS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: MPP3 (Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) (MPP3))

Alternative Name: Mpp3 (MPP3 Products)

Background: MAGUK p55 subfamily member 3 (Discs large homolog 3) (Protein MPP3),FUNCTION: Participates in cell spreading through the phosphoinositide-3-kinase (PI3K) pathway by connecting CADM1 to DLG1 and the regulatory subunit of phosphoinositide-3-kinase (PI3K) (By similarity). Stabilizes HTR2C at the plasma membrane and prevents its desensitization (PubMed:16914526). May participates in the maintenance of adherens junctions (PubMed:23893895, PubMed:23658188). {ECO:0000250|UniProtKB:Q13368, ECO:0000269|PubMed:16914526, ECO:0000269|PubMed:23658188, ECO:0000269|PubMed:23893895}.

Molecular Weight: 64.4 kDa

UniProt: O88910

AlphaFold: O88910