Cytokeratin 13 Protein (AA 1-437) (His tag)

Catalog No. ABIN7562762

This Recombinant Cytokeratin 13 protein is expressed in HEK-293 Cells.

Quick Overview for Cytokeratin 13 Protein (AA 1-437) (His tag) (ABIN7562762)

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-437

Purification tag / Conjugate: This Cytokeratin 13 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Krt13 Protein expressed in mammalian cells.

Sequence: MSCRFQSSSM SYGGGFGAGS CQLGGGRNIS SCSSRFVTGG SAGGYGGGMS CGFGGGAGGG FGGGFGGGFG GSYGGGFGGG FGDFGGVDGG LLSGNEKITM QNLNDRLASY LDKVRALEAA NADLEVKIRD WHLKQSPASP ERDYSAYYKT IEELRIKILE ATTDNNRIIL EIDNARLAAD DFRLKYENEL TLRQSVEADI NGLRRVLDEL TLAKTDLEMQ IESLNEELAY LKKNHEEEMK EFSNQVVGQV NVEMDATPGI DLTRVLAEMR EQYEALAEKN RRDAEEWFQT KSAELNKEVS SNAEMIQTSK TEITELRRTL QGLEIELQSQ LSMKAGLEST LAETECRYAL QLQQIQGLIS SIEAQLSELR SEMECQNQEY KMLLDIKTRL EQEIATYRSL LEGQDAKMTG FNSGGNNTTT SNGSPSSNSG RPDFRKY Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Alternative Name: Krt13

Background: Keratin, type I cytoskeletal 13 (47 kDa cytokeratin) (Cytokeratin-13) (CK-13) (Keratin-13) (K13),FUNCTION: Type 1 keratin (Probable). Maintains postnatal tongue mucosal cell homeostasis and tissue organization in response to mechanical stress, potentially via regulation of the G1/S phase cyclins CCNE1 and CCNE2 (PubMed:32758484). {ECO:0000269|PubMed:32758484, ECO:0000305}.

Molecular Weight: 47.8 kDa

UniProt: P08730

AlphaFold: P08730