ENPEP Protein (AA 1-945) (His tag)

Catalog No. ABIN7562904

Recombinant ENPEP protein expressed in HEK-293 Cells.

Quick Overview for ENPEP Protein (AA 1-945) (His tag) (ABIN7562904)

Target: ENPEP (Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-945

Purification tag / Conjugate: This ENPEP protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Enpep Protein expressed in mammalian cells.

Sequence: MNFAEEEPSK KYCIKGKHVA IICGVVVAVG LIVGLSVGLT RSCEQDTTPA PSQPPPEAST ALPPQDQNVC PDSEDESGEW KNFRLPDFIN PVHYDLEVKA LMEEDRYTGI VTISVNLSKP TRDLWLHIRE TKITKLPELR RPSGEQVPIR RCFEYKKQEY VVIQAAEDLA ATSGDSVYRL TMEFKGWLNG SLVGFYKTTY MEDGQIRSIA ATDHEPTDAR KSFPCFDEPN KKSTYSISII HPKEYSALSN MPEEKSEMVD DNWKKTTFVK SVPMSTYLVC FAVHRFTAIE RKSRSGKPLK VYVQPNQKET AEYAANITQA VFDYFEDYFA MEYALPKLDK IAIPDFGTGA MENWGLVTYR ETNLLYDPLL SASSNQQRVA SVVAHELVHQ WFGNTVTMDW WDDLWLNEGF ASFFEFLGVN HAEKDWQMLS QVLLEDVFPV QEDDSLMSSH PVVVTVSTPA EITSVFDGIS YSKGASILRM LQDWITPEKF QKGCQIYLKK FQFANAKTSD FWDSLQEASN LPVKEVMDTW TSQMGYPVVT VSGRQNITQK RFLLDSKADP SQPPSELGYT WNIPVRWADN DNSRITVYNR LDKGGITLNA NLSGDAFLKI NPDHIGFYRV NYEGGTWDWI AEALSSNHTR FSAADRSSFI DDAFALARAQ LLNYKIALNL TMYLKSEEDF LPWERVISSV SYIISMFEDD RELYPMIETY FQGQVKPVAD LLGWQDTGSH ITKLLRASIL GFACKMGDRE ALGNASQLFD SWLKGSASIP VNLRLLVYRY GMQNSGNEAA WNYTLEQYQK TSLAQEKEKL LYGLASVKDV KLLARYLEML KDPNIIKTQD VFTVIRYISY NSYGKTMAWN WIQLNWDYLV SRFTINDRYL GRIVTIAEPF NTELQLWQMQ SFFAKYPNAG AGAKPREQVL ETVKNNIEWL NVNRQSIREW FASLP Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ENPEP (Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP))

Alternative Name: Enpep

Background: Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (BP-1/6C3 antigen) (CD antigen CD249),FUNCTION: Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II. {ECO:0000250|UniProtKB:Q07075}.

Molecular Weight: 108.0 kDa

UniProt: P16406

AlphaFold: P16406

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones