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DPP4 Protein (AA 1-760) (His tag)

This Recombinant DPP4 protein is expressed in HEK-293 Cells.
Catalog No. ABIN7563068

Quick Overview for DPP4 Protein (AA 1-760) (His tag) (ABIN7563068)

Target

See all DPP4 Proteins
DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Protein Type

Recombinant

Origin

  • 21
  • 5
  • 3
  • 2
  • 1
  • 1
Mouse

Source

  • 16
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade

custom-made
  • Protein Characteristics

    AA 1-760

    Purification tag / Conjugate

    This DPP4 protein is labelled with His tag.

    Purpose

    Predefined custom protein recombinant Dpp4 Protein expressed in mammalian cells.

    Sequence

    MKTPWKVLLG LLGVAALVTI ITVPIVLLSK DEAAADSRRT YSLADYLKST FRVKSYSLWW VSDFEYLYKQ ENNILLLNAE HGNSSIFLEN STFESFGYHS VSPDRLFVLL EYNYVKQWRH SYTASYNIYD VNKRQLITEE KIPNNTQWIT WSPEGHKLAY VWKNDIYVKV EPHLPSHRIT STGEENVIYN GITDWVYEEE VFGAYSALWW SPNNTFLAYA QFNDTGVPLI EYSFYSDESL QYPKTVWIPY PKAGAVNPTV KFFIVNIDSL SSSSSAAPIQ IPAPASVARG DHYLCDVVWA TEERISLQWL RRIQNYSVMA ICDYDKINLT WNCPSEQQHV EMSTTGWVGR FRPAEPHFTS DGSSFYKIIS DKDGYKHICH FPKDKKDCTF ITKGAWEVIS IEALTSDYLY YISNQYKEMP GGRNLYKIQL TDHTNVKCLS CDLNPERCQY YAVSFSKEAK YYQLGCWGPG LPLYTLHRST DHKELRVLED NSALDRMLQD VQMPSKKLDF IVLNETRFWY QMILPPHFDK SKKYPLLLDV YAGPCSQKAD ASFRLNWATY LASTENIIVA SFDGRGSGYQ GDKIMHAINR RLGTLEVEDQ IEAARQFVKM GFVDSKRVAI WGWSYGGYVT SMVLGSGSGV FKCGIAVAPV SRWEYYDSVY TERYMGLPIP EDNLDHYRNS TVMSRAEHFK QVEYLLIHGT ADDNVHFQQS AQISKALVDA GVDFQAMWYT DEDHGIASST AHQHIYSHMS HFLQQCFSLH Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

    Specificity

    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

    Characteristics

    Key Benefits:
    • Predefined custom protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
  • Want other Options for this Protein ?

    !
    Discover Our Catalog and Custom Protein Service Options!
    Product
    Expression System
    Conjugate
    Origin
    Price
    Expression System Escherichia coli (E. coli)
    Conjugate His tag
    Origin Mouse
    Price $663.94
    Expression System Escherichia coli (E. coli)
    Conjugate His tag
    Origin Mouse
    Price $420.00
    Expression System Escherichia coli (E. coli)
    Conjugate His tag
    Origin Mouse
    Price $450.00
    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Mouse
    Price $571.54

    Your project requires further customization? Contact us and discover our custom protein solutions

  • Application Notes

    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    The buffer composition is at the discretion of the manufacturer.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C.

    Expiry Date

    12 months
  • Target

    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

    Alternative Name

    Dpp4

    Background

    Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form), Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)],FUNCTION: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. {ECO:0000250|UniProtKB:P27487}.

    Molecular Weight

    87.4 kDa

    UniProt

    P28843

    AlphaFold

    P28843

    Pathways

    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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