Adiponectin Receptor 2 Protein (ADIPOR2) (AA 1-386) (His tag)

Catalog No. ABIN7564411

This Recombinant Adiponectin Receptor 2 protein is produced in HEK-293 Cells.

Quick Overview for Adiponectin Receptor 2 Protein (ADIPOR2) (AA 1-386) (His tag) (ABIN7564411)

Target: Adiponectin Receptor 2 (ADIPOR2)

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-386

Purification tag / Conjugate: This Adiponectin Receptor 2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Adipor2 Protein expressed in mammalian cells.

Sequence: MNEPAKHRLG CTRTPEPDIR LRKGHQLDDT RGSNNDNYQG DLEPSLETPV CSSYYENSPE EPECHDDNSQ EDEGFMGMSP LLQAHHAMER MEEFVCKVWE GRWRVIPHDV LPDWLKDNDF LLHGHRPPMP SFRACFKSIF RIHTETGNIW THLLGCVFFL CLGIFYMFRP NISFVAPLQE KVVFGLFFLG AILCLSFSWL FHTVYCHSEG VSRLFSKLDY SGIALLIMGS FVPWLYYSFY CNPQPCFIYL IVICVLGIAA IIVSQWDMFA TPQYRGVRAG VFVGLGLSGI IPTLHYVISE GFLKAATIGQ IGWLMLMASL YITGAALYAA RIPERFFPGK CDIWFHSHQL FHIFVVAGAF VHFHGVSNLQ EFRFMIGGGC TEEDAL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Adiponectin Receptor 2 (ADIPOR2)

Alternative Name: Adipor2

Background: Adiponectin receptor protein 2 (Progestin and adipoQ receptor family member 2) (Progestin and adipoQ receptor family member II),FUNCTION: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:17327425, PubMed:17068142, PubMed:17268472, PubMed:24742672). Required for normal body fat and glucose homeostasis (PubMed:17327425, PubMed:17068142, PubMed:17268472, PubMed:24742672). ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake (PubMed:12802337, PubMed:17268472, PubMed:24742672). Has intermediate affinity for globular and full-length adiponectin (PubMed:12802337). Required for normal revascularization after chronic ischemia caused by severing of blood vessels (PubMed:24742672). {ECO:0000269|PubMed:12802337, ECO:0000269|PubMed:17068142, ECO:0000269|PubMed:17268472, ECO:0000269|PubMed:17327425, ECO:0000269|PubMed:24742672}.

Molecular Weight: 44.0 kDa

UniProt: Q8BQS5

AlphaFold: Q8BQS5

Pathways: AMPK Signaling