CADPS2 Protein (AA 1-1297) (His tag)

Catalog No. ABIN7564469

This Recombinant CADPS2 protein is expressed in HEK-293 Cells.

Quick Overview for CADPS2 Protein (AA 1-1297) (His tag) (ABIN7564469)

Target: CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1297

Purification tag / Conjugate: This CADPS2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Cadps2 Protein expressed in mammalian cells.

Sequence: MLDPSSSEEE SDEGLEEESR EVLVAPGVSQ RAPPAAAREG RRDAPGRSGG GSGGGAARPV SPSPSVLSEG RNEPELQLDE EQERRIRLQL YVFVVRCIAY PFNAKQPTDM ARRQQKLNKQ QLQLLKERFQ AFLNGETQIV ADEAFCNAVR SYYEVFLKSD RVARMVQSGG CSANDFREVF KKNIEKRVRS LPEIDGLSKE TVLSSWIAKY DAIYRGEEDL CKQPNRMTLS AVSELILSKE QLYEMFQQIL GIKKLEHQLL YNACQLDNAD EQAAQIRREL DGRLQLAEKM AKERRFPRFI SKEMESMYIE ELRASVNLLM ANLESLPVSK GGPEFKLQKL KRSQNSAFLD LGDENEIQLS KSDVVLSFTL EIVIMEVQGL KSVAPNRIVY CTMEVEGGEK LQTDQAEASR PQWGTQGDFN TTHPRPVVKV KLFTESTGVL ALEDKELGRV VLYPTSNSSK SAELHRMTVP KNSQDSDLKI KLAVRMDKPA HMKHSGYLYA LGQKVWKRWK KRYFVLVQVS QYTFAMCSYR EKKSEPQELM QLEGYTVDYT DPHPGLQGGQ VFFNAVKEGD TVIFASDDEQ DRILWVQAMY RATGQSYKPV PAVQSQKLNP KGGALHADAQ LYADRFQKHG MDEFISASPC KLDHAFLFRI LQRQTLDHRL NDSYSCLGWF SPGQVFVLDE YCARYGVRGC HRHLCYLTEL MEHSENGAVI DPTLLHYSFA FCASHVHGNR PDGIGTVSVE EKERFEEIKD RLSSLLENQI SHFRYCFPFG RPEGALKATL SLLERVLMKD IATPIPAEEV KKVVRKCLEK AALINYTRLT EYAKIEETMN QATPARKLEE VLHLAELCIE VLQQNEEHHA EGREAFAWWP DLLAEHAEKF WALFTVDMDT ALEAQPQDSW DSFPLFQLLN NFLRNDTLLC NGKFHKHLQE IFVPLVVRYV DLMESAIAQS IHRGFEQETW QPVKNIANSL PNVALPKVPS LPLNLPQIPS FSTPPWMASL YESTNGSTTS EDLFWKLDAL QMFVFDLHWP EQEFAHHLEQ RLKLMASDMI EACVKRTRTA FELKLQKANK TTDLRIPASV CTMFNVLVDA KKQSTKLCAL DGGQEQQYHS KIDDLIDNTV KEIIALLVSK FVSVLEGVLS KLSRYDEGTF FSSILSFTVK AAAKYVDVPK PGMDLADTYI MFVRQNQDIL REKVNEEMYI EKLFDQWYSN SMKVICVWLA DRLDLQLHIY QLKTLIKIVK KTYRDFRLQG VLEGTLNSKT YDTLHRRLTV EEATASVSEG GGLQGITMKD SDEEEEG Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))

Alternative Name: Cadps2

Background: Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2),FUNCTION: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles.

Molecular Weight: 147.8 kDa

UniProt: Q8BYR5

AlphaFold: Q8BYR5

Pathways: Synaptic Vesicle Exocytosis