AQR Protein (AA 1-1481) (His tag)

Catalog No. ABIN7564560

Recombinant AQR protein expressed in HEK-293 Cells.

Quick Overview for AQR Protein (AA 1-1481) (His tag) (ABIN7564560)

Target: AQR (Aquarius Homolog (AQR))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1481

Purification tag / Conjugate: This AQR protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Aqr Protein expressed in mammalian cells.

Sequence: MAAPAQPKKI VAPTVSQINA EFVTQLACKY WAPHIKKKSP FDIKVIEEIY EKEIVKSRFA IRKIMLLEFS QYLENYLWMN YSPEVSSKAY LMSICCMVNE KFRENVPAWE TFKKKPDHFP FFFKCILKAA LAETDGEFSL HEQTLLLLFL DHCFNSLEVD LIRSQVQQLI SLPMWMGLQP ARLELELKKT PKLRKFWNLI KKNDEKMDPE AREQAYQERR FLSRLIQKFI SVLKSIPLSE PVTMDKVHYC ERFIELMIDL EALLPTRRWF NTILDDSHLL VHCYLSSLVH REEDGHLFSQ LLDMLKFYTG FEINDQTGNA LTENEMTTIH YDRITSLQRA AFAHFPELYD FALSNVAEVD ARDSLVKFFG PLSSNTLHQV ASYLCLLPTL PKNEDTTFDK EFLLELLVSR HERRISQIQQ LNQMPLYPTE KIIWDENIVP TEYYSGEGCL ALPKLNLQFL TLHDYLLRNF NLFRLESTYE IRQDIEDSVS RMKPWQSEYG GVVFGGWARM AQPIVAFTVV EVAKPNIGEN WPTRVRADVT INLNVRDHIK DEWEGLRKHD VCFLITVRPT KPYGTKFDRR RPFIEQVGLV YVRGCEIQGM LDDKGRVIED GPEPRPNLRG ESRTFRVFLD PNQYQQDMTN TIQNGAEDVY DTFNVIMRRK PKENNFKAVL ETIRNLMNTD CVVPDWLHDI ILGYGDPSSA HYSKMPNQIA TLDFNDTFLS IEHLKASFPG HNVKVTVSDP ALQIPPFRIT FPVRSGKGKK RKDADGEEDD TEEAKTLIVE PHVIPNRGPY PYNQPKRNTI QFTHTQIEAI RAGMQPGLTM VVGPPGTGKT DVAVQIISNI YHNFPEQRTL IVTHSNQALN QLFEKIMALD IDERHLLRLG HGEEELETEK DFSRYGRVNY VLARRIELLE EVKRLQKSLG VPGDASYTCE TAGYFFLYQV MSRWEEYMSR VKNSGTACPD AAPDAAQVAT FFPFHEYFAN APQPIFKGRS YEEDMEIAEG CFRHIKKIFT QLEEFRASEL LRSGLDRSKY LLVKEAKIIA MTCTHAALKR HDLVKLGFKY DNILMEEAAQ ILEIETFIPL LLQNPQDGFS RLKRWIMIGD HHQLPPVIKN MAFQKYSNME QSLFTRFVRV GVPTVDLDAQ GRARASLCNL YNWRYKNLGN LPHVQLLPEF STANAGLLYD FQLINVEDFQ GVGESEPNPY FYQNLGEAEY VVALFMYMCL LGYPADKISI LTTYNGQKHL IRDIINRRCG NNPLIGRPNK VTTVDRFQGQ QNDYILLSLV RTRAVGHLRD VRRLVVAMSR ARLGLYIFAR VSLFQNCFEL TPAFSQLTAR PLHLHIIPTE PFPTSRKNGE RPPHEVQVIK NMPQMANFVY NMYMHLIQTT HHYHQTFLQL PPAMVEEGEE GQSQETEMEA EEETVSAQGN LTPSPADASL SQETPAAQPD CSSQTEDTSA PCDIATAAEP VSAAAEAATP QDAESVPTET E Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: AQR (Aquarius Homolog (AQR))

Alternative Name: Aqr

Background: RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa),FUNCTION: Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro). {ECO:0000250|UniProtKB:O60306}.

Molecular Weight: 170.3 kDa

UniProt: Q8CFQ3

AlphaFold: Q8CFQ3