RGS12 Protein (AA 1-1381) (His tag)

Catalog No. ABIN7564570

Product Details

Target: RGS12 (Regulator of G-Protein Signalling 12 (RGS12))

Protein Type: Recombinant

Protein Characteristics: AA 1-1381

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This RGS12 protein is labelled with His tag.

Purpose: Made-to-order recombinant Rgs12 Protein expressed in mammalian cells.

Sequence: MYRAGEPGKR QPGPAPPRVR SVEVARGRAG YGFTLSGQAP CVLSCVMRGS PADFVGLRAG DQILAINEIN VKKASHEDVV KLIGKCSGVL HMVIAEGTSH VESCSSDEEG GLYEGKGWLR PKLDSKALGI NRAERVVEEV QSGGIFNMIF ESSSLCASGP EPLKLKQRSL SESAALRLDA GQAGLCAPHP SMLSKEDISK VINDDSVFTV GLDSHDDFGL DASILNVAMV VGYLGSIELP STSSNLEHDS LQAIRGCMRR LRAEQKIHSL VTMKVMHDCV QLVTDRAGVV AEYPAEKLAF SAVCPDDRRF FGLVTMQTND DGGLAQEDEG ALRTSCHVFM VDPDLFHHKI HQGIARRFGF ACTADPDTSG CLEFPASSLP VLQFISVLYR DMGELIEGVR ARAFLDGDAD AHQNNSTSSN SDSGIGNFNQ EEKSNRVLVV DLGGGSSRHG QGSSPGWESG GGRGSQPWSA PWNGAFCHDS EAGSPLETSP NTDRFWDLTK HSGPVSHMEV PPATLRSSIP PSKRGAAGSS CGFNQRWLPV HVLQEWQCGH ASDQESYTDS TDGWSSVNCG TLPPPMSKIP ADRYRVEGSF AQAPLSTQKR DWSRKAFGMQ NLFGPHRNVR KTKEDKKSSK LGRGVALAQT SQRTSARRSF GRSRRFSITR SLDDLESATV SDGELTGADL KDCISNNSLS SNASLPSVQS CRRLRERRVA SWAVSFERLL QDPVGVRYFS DFLRKEFSEE NILFWQACEC FSHVPAHDKK ELSYRAREIF SKFLCSKATT PVNIDSQAQL ADDILNAPHP DMFKEQQLQI FNLMKFDSYT RFLKSQLYQE CVLAEVEGRT LPDSQQVPSS PASKHSISSD HSNVSTPKKL SGKSKSGRSL NEDVGEEDSE KKRRGAFFSW SRSRSTGRSQ KKKDHGDHAH DAPHANGGLC RRESQGSVSS AGSLDLSEAC RTSALEKDKA AKHCCVHLPD GTSCVVAVKS GFSIKEILSG LCERHGINGA AVDLFLVGGD KPLVLHQDSS ILATRDLRLE KRTLFRLDLV PINRSVGLKA KPTKPVTEVL RPVVAKYGLD LGSLLVRLSG EKEPLDLGAP ISSLDGQRVI LEERDPSRGK VSTDKQKGAP VKQNSAVNSS PRNHLAMGEE RTLGKSNSIK IRGENGKSAR DPRLSKREES IAKIGKKKYQ KINLDEAEEF FELISKAQSN RADDQRGLLR KEDLVLPEFL RLPAGSSELA LSSPPPVKGY SKRAVTGHGQ EGAAQTEESY SDSPATSPAS AQSPCSAYSP GSAHSPGSAH STPGPPGTTQ PGEKPTKPSC VSMVQEGTTQ AWRRLSPEME AGGIQTVEDE QVADLTLMGE GDISSPNSTL LPPPPTPQDT PGPPRPGTSR F Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: RGS12 (Regulator of G-Protein Signalling 12 (RGS12))

Alternative Name: Rgs12 (RGS12 Products)

Background: Regulator of G-protein signaling 12 (RGS12),FUNCTION: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. {ECO:0000250|UniProtKB:O08774}.

Molecular Weight: 149.6 kDa

UniProt: Q8CGE9

AlphaFold: Q8CGE9

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling