ATXN7 Protein (AA 1-867) (His tag)

Catalog No. ABIN7564711

This Recombinant ATXN7 protein is produced in HEK-293 Cells.

Quick Overview for ATXN7 Protein (AA 1-867) (His tag) (ABIN7564711)

Target: ATXN7 (Ataxin 7 (ATXN7))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-867

Purification tag / Conjugate: This ATXN7 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Atxn7 Protein expressed in mammalian cells.

Sequence: MSERAADDVR GEPRRAAGGA AAARQQQQQP QPLQPQRQHP PLRRPRAEDG GTGDTTTSAA AMATVGERRP LPSPEAMLGQ SWNLWVEASK LPGKDGTELD ESFKEFGKNR EVMGLCREDM PIFGLCPAHD DFYLVVCNDC NQVVKPQAFQ SHYERRHSSS SKPALAVPHT SVFSLLPSLS KSKGSGAGGS SRPPSGGVLC ASSSSKLLRL PKEKLPLRGN MKPMHPVQQI KVPHGRVMTP SVKVEKMHPK MDGTLLKSTV GPACPATMSS AVKPGLNCPS IPKPTLPSPG QILNGKGLPA MPTLEKKSED SSNNRKFLNK RLSEREFDPD IHCGVIDLDT KKPCTRSLTC KTHSLTQRRA VQGRRKRFDV LLAEHKNKAR EKELIRHDSQ QVPHPLRDPH PTPPRTPQEP QLPAESKPFL ASKPKPQTPS LPRPPGCPAQ QGGSTPIDPP PGQESPHPPL PATEPASRLS SEEGEGDDRE ESVEKLDCHY SGRHPQPASF CTFGSRQIGR GYYVFDSRWN RLRCALNLMV EKHLNAQLWK KIPPVPCTTS PVSARVPHRT NSVPTSQGGI SYLAATTVSA PPVLLSSTCI SPNSKSVPAH GTTLNAQPAG SGAMDPVCSV QSRQVSASSS PPSTPSGLSS VPSSPLSRKP QKWKPSKSIR PKESSALSTN CHNASSSTSG GSGKKRKNSS PLLVPSSSSS SSSSSSSSHS VNSFRKNCVA HSGTPYLSTA PSSHSIGLNC VTNKTHSVSL RHEQAGRGPA GVSSAEPIKR MSVMVNSSDS TLSLGPFIHQ ASELPVNPHS HTPLDKLIGK KRKCSPGSST VGNSGSKPTK VAKLPAMNNV HMKHTGNISG AQGLTNNSLL HQPKARP Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ATXN7 (Ataxin 7 (ATXN7))

Alternative Name: Atxn7

Background: Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog),FUNCTION: Involved in neurodegeneration. Acts as a component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation (By similarity). Necessary for microtubule cytoskeleton stabilization (By similarity). {ECO:0000250|UniProtKB:O15265}.

Molecular Weight: 92.7 kDa

UniProt: Q8R4I1

AlphaFold: Q8R4I1