BANP Protein (AA 1-548) (His tag)

Catalog No. ABIN7564721

This Recombinant BANP protein is expressed in HEK-293 Cells.

Quick Overview for BANP Protein (AA 1-548) (His tag) (ABIN7564721)

Target: BANP (Protein BANP (BANP))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-548

Purification tag / Conjugate: This BANP protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Banp Protein expressed in mammalian cells.

Sequence: MMSEQDLADV VQIAVEDLSP DHPVVLENHV VTDDDEPALK RQRLEINCQD PSIKSFLYSI NQTICLRLDS IEAKLQALEA TCKSLEEKLD LVTNKQHSPI QVPMVAGSPL GATQTCNKVR CVVPQTTVIL NNDRQNAIVA KMEDPLSNRA PDSLENIISN AVPGRRQNTI VVKVPGQDDS HNEDGESGSE ASDSVSNCGQ PGSQNIGSNV TLITLNSEED YPNGTWLGDE NNPEMRVRCA IIPSDMLHIS TNCRTAEKMA LTLLDYLFHR EVQAVSNLSG QGKHGKKQLD PLTIYGIRCH LFYKFGITES DWYRIKQSID SKCRTAWRRK QRGQSLAVKS FSRRTPSSSS YSASETMMGT PPPTSELQQS QPQALHYALA NAQQVQIHQI GEDGQVQVIP QGHLHIAQVP QGEQVQITQD SEGNLQIHHV GQDGQSWGLC QNPIPVSGDS VAQANPSQLW PLGGDTLDLP AGNEMIQVLQ GAQLIAVASS DPAATGVDGS PLQGSDIQVQ YVQLAPVSDH TAAAQTAEAL QPTLQPDMQL EHGAIQIQ Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: BANP (Protein BANP (BANP))

Alternative Name: Banp

Background: Protein BANP (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein),FUNCTION: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest and inhibits tumor growth (PubMed:12494467). {ECO:0000269|PubMed:10950932, ECO:0000269|PubMed:12494467, ECO:0000269|PubMed:15371550, ECO:0000269|PubMed:15623522, ECO:0000269|PubMed:16166625, ECO:0000269|PubMed:17229733}.

Molecular Weight: 59.7 kDa

UniProt: Q8VBU8

AlphaFold: Q8VBU8