SYNPO2 Protein (AA 1-1087) (His tag)

Catalog No. ABIN7564821

Recombinant SYNPO2 protein expressed in HEK-293 Cells.

Quick Overview for SYNPO2 Protein (AA 1-1087) (His tag) (ABIN7564821)

Target: SYNPO2 (Synaptopodin 2 (SYNPO2))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1087

Purification tag / Conjugate: This SYNPO2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Synpo2 Protein expressed in mammalian cells.

Sequence: MGTGDFICIS MTGGAPWGFR LQGGKEEQQP LQVAKIRSQS KASGSGLREG DEVVSINGNP CADLTYPEVI KLMEGITDSL HLLVKRPSSG TSETLDSESE TTNHQHLTHE GPMESTTLQI QQATETQSED FFLAPVQTKV PLTEDQSNAW GYAECPKEEQ APPMLGSQEG HLVEEVILRQ KAEAGQPGHV VELQLSLSKE RHQCTSGPIV TLQGNDKSTS PDPDWSSQLE RTVHINSIPA PEKADTSLTS STSSGRELRV IQGRDPGGAG LPQVEVILDC SDRLKAEECR LQTGRGCVAS PVEGGRSEAP PSLVSFAVSS EGTEHGEDQR SGKDQSRPHK HRARHARLRR SESLSEKQVK EAKSKCKSIA LLLTDAPNPN SKGVLMFKKR RRRARKYTLV SYGTGELERE EEEEEDQEAG DKDEISEVAF LGTSESEVDE ELLSDVDDNT QVVNFDWDSG LVDIEKRLNR GDKMEMLPDT TGKGALMFAK RRERMEQFTA QNEEEKTGGM AGGGPDALQT DGLRTMTSYQ RKEESVRMQS SVSESSFQMG RSLASVPQQN GFSGVSETAG AQRMFPMNRT AKPFLGSMNQ PAAPFSPTRS VTSPISDFPA PPPYSAVSPP PEAFSRGVSS PVAGPAQPPP WPQPAPWSQP AFYDSSEQIA SRDERIAVPA KRTGILQEAK RRGTTKPMFT FKETKVSPNP ELLSLLQNAE GKRGTGGDSG PEEDYLSLGA EACNFMQSSA KQKTPPPVAP KPAVKSPSSS QPVAPVSPVW SPGVAPAQRP AFSTSNPPNP PQVTAVSSIK IAQPAAPPAR PASALNLAGP FKGPQAVVVS HNYTPKPSAP TPLVNAAPAG AGGPSNELPG MSGKGAQLFA KRQSRMEKYV VDSDTVQAHT VRAQSPTPSL PASWKYSSNV RAPPPVAYNP IHSPSYPLAA IKSQPPGAQA SKTSKKKGKK PLNTLDVMKH QPYQLNASLF TFQPPDSKDG LPQKSTVKVS SAPAMKQALP PRQANVGSPT NAQASSVYSV PAYTSQPNFF AAEATSPVSA SPVPVSVPTS PKQESTSTSY FVAPRPKFSA KKSGVTVQVW KPSVVEE Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SYNPO2 (Synaptopodin 2 (SYNPO2))

Alternative Name: Synpo2

Background: Synaptopodin-2 (Myopodin),FUNCTION: Has an actin-binding and actin-bundling activity (PubMed:11673475). Can induce the formation of F-actin networks. At the sarcomeric Z lines is proposed to act as adapter protein that links nascent myofibers to the sarcolemma via ZYX and may play a role in early assembly and stabilization of the Z lines. Involved in autophagosome formation. May play a role in chaperone-assisted selective autophagy (CASA) involved in Z lines maintenance in striated muscle under mechanical tension, may link the client-processing CASA chaperone machinery to a membrane-tethering and fusion complex providing autophagosome membranes. Involved in regulation of cell migration. May be a tumor suppressor (By similarity). {ECO:0000250|UniProtKB:D4A702, ECO:0000250|UniProtKB:Q9UMS6, ECO:0000269|PubMed:11673475}.

Molecular Weight: 116.5 kDa

UniProt: Q91YE8

AlphaFold: Q91YE8