SYCP2 Protein (AA 1-1500) (His tag)

Catalog No. ABIN7564949

This Recombinant SYCP2 protein is expressed in HEK-293 Cells.

Quick Overview for SYCP2 Protein (AA 1-1500) (His tag) (ABIN7564949)

Target: SYCP2 (Synaptonemal Complex Protein 2 (SYCP2))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1500

Purification tag / Conjugate: This SYCP2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Sycp2 Protein expressed in mammalian cells.

Sequence: MPVRPDLQQL EKCIDDALRK NDFKPLLALL QIDICEDVKI KCSKQFLRKL DDLICRELNK KDIQTVSSIL ISIGRCSKNI FILGQAGLQT MIKQGLVQKM VSWFENSKEI ILNQQQSKDE AVMNMIEDLF DLLMVIYDIS DEGKNQVLES FIPQICALVI DSRVNFCIQQ EALKKMNLML DRIPQDANKI LSNQEMLTLM SNMGERILDV GDYELQVGIV EALCRMTTEK RRQELAYEWF SMDFIANAFK EIKDCEFETD CRIFLNLVNG ILGDKRRVYT FPCLSAFLGK YELQIPSDEK LEEFWIDFNL GSHTLSFYIA GDEEDHQWEA VTVPEEKVQM YNIEVRESKK LLTLTLKNIV KISKKEGKEL LFYFDESLEI TNVTKKVFGG NKYKEFTRKQ GISVAKTSIH VLFDASGSQI LVPESQPSPV KENLIHLKEK SDIQKKLVNP LELGNSSSQD EITTPSRKKM SEASMIVPDT DRYTVRSPIL LINTSTPRRS REPLQAINSV EKAVSKTSES GMDYAASPKS RQSDGRKRWN NRANHNKTTA VIQNKQYEDN ESPDQNFNEI EDTLSNVSSA VGKVDKPVLP GVLDISKNTT HSRWACWTPV TTIKLCNNQR SRALPGDTCT QDTGVNKKCT KQKSVSDDDS EETQKGKYSK DVIKCNKSDE AEFCERNIQE QNHPKYSQKK NTANAKKSDW HIESETTYKS VLLNKTTEES LIYKKTCVLS KDVNTTICDK SPSRKSKRNH TKSRKELMSE LTSCELEEIP VRENSKGKRF TGASESLINQ ISRRYNPSDS MMSTRKLKEP QDGSGFSKKP DLQFNKVQRK SYRKLKATVV NVTSECPLDD VYNFSLNGAD EPVIKLGIQE FQATTREASM DNSLKLVKNH DEHDPFLKTK DKRMLSYEKK TLLSDTETEC GCDDSKTDIS WLKEPKTKRL MDYSRNKNTT KYKSRKSRSS MEKGQPRPTM VLNKNSMKND YEVVVDGRTR LPRRATKTKK NYKDLSTSES ESESEKECSY LFKDKLPTKE ETIHSRAQTK KLPEKQQKVF NSEALKGQPS EEQKNSSRLR EGREDSLCLS SASVSRSSSS VEVMRCTEKI TERDFTQDYD YITKSLSPYP KAPSPEFLNG NNSVVGRGQS PRISETSAMC VRKSYSPASG PPFSPRHTPT KNNSVVNMKK ANSVINNQRT QHCNSYSDVS SNSSEKLYME PESPESCDNH MQNKREGNHA ASPLSLSSEK IEKMWFDMPS ENTHVSGPSQ RGSKRRMYLE DDELSNSNEA EVEEAEEREH LLSKKRCQWE NSDQHTFKTS LSTPDFSVPK DWQQELQGAG MFYDNISSDY KRKTDSQHKI MDDFTTKTLK LTQQHLMAMT SQAQGRRDEN VEKFQVTLLD ELEKVEKDSQ TLRDLEKELV DIEEKLVQKM RAYHRCERER FRVLKTSLDK SFLVYNSVYE ESVFTSEMCL MKANMKMLQD KLLKEMHEEE VLNIRRGLQS LFKAHEGNDA Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SYCP2 (Synaptonemal Complex Protein 2 (SYCP2))

Alternative Name: Sycp2

Background: Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein),FUNCTION: Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes (PubMed:16717126). Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility (PubMed:16717126). Required for insertion of SYCP3 into synaptonemal complexes (PubMed:16717126). May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements. {ECO:0000269|PubMed:11463847, ECO:0000269|PubMed:16717126}.

Molecular Weight: 172.1 kDa

UniProt: Q9CUU3

AlphaFold: Q9CUU3

Pathways: M Phase