CCDC39 Protein (AA 1-937) (His tag)

Catalog No. ABIN7564988

This Recombinant CCDC39 protein is expressed in HEK-293 Cells.

Quick Overview for CCDC39 Protein (AA 1-937) (His tag) (ABIN7564988)

Target: CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-937

Purification tag / Conjugate: This CCDC39 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Ccdc39 Protein expressed in mammalian cells.

Sequence: MCSEFLSELH WEDGFAIPVA NQENKILEDQ LAKLREEKSN LQDQLHDYEE RINSMTSHLK NVNQEFLFTQ SLYKARESEI ESEEHFKAIA ERELGRVKNE TQLLEKEMAI IRERKSQMEN NIFKTTQKLD DLKCQMNWDQ QALEAWLEES AHKDSDSLTL QKYSQQDDNK IRALTLQLEK LTMEYNEKRK LLDSELTETL SAQLELDKAA QDFRKIHLER QELIQQWENT IEQMQRRDQE IDNCALALSR IKQEAREKEG VVKEKIKFLE NEVENNIEYE RKISVAERKV SKCRMDYQRH EGNRSQLKDE LDTLKTTLNR TSSDLQALRK NISKVKKDIF DETLRLQKLK HHNEVVKHKL KMITEKTLSI EEKATNMEDM LKEEEKGLKE VEVQLGIVKD VLFKKVQELQ NEIAKEKALV SEIEGTRSSL KHLNKQLHKL DFETLKQQEI MYSQDFYIQQ VERRMSRLKG EINSEEKQAL EAKILELKKT MDEKKSTLSL LESQIKKLHN DLYFIKKSNG KNNDEKESLM NKISELNLFI DRSEKELSKA KAVKEDMMIE DNLLKLQVKR ARELLYSKAE EVLSLEKRKQ QLGKDMEERA EEIKVHKAML TSQIRCVEQQ RKTMSSEFHE RLSKIDKLKN RYEILTVVML PPEGEEEKTQ SYYVIKAAQE KEELQREGDS LDAKINKAEK EIYALQNTLQ VLNSCNSNYK QSFKKVTPSS DEYALKIQLE EQKRTADERY RCKQRQIREL QEDIQSMENT FEVIGHLANN AKEKLTEKQT LAFQLRKETE EQKPKLQRIT KQCGRLRREI RILKQTDNET LEEQDIQLRE IIQFHKDIDQ MLVNAMENAE IHAIFKTYFE QNGLELPTAR GPSSRSSSQS SSLSSFRSLE DVTLQSPPTA KVIQLRFPEP PPATNDSSRS ASSGSNSNIP KEKKLSK Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))

Alternative Name: Ccdc39

Background: Coiled-coil domain-containing protein 39,FUNCTION: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. {ECO:0000250|UniProtKB:A8IQT2, ECO:0000250|UniProtKB:Q9UFE4}.

Molecular Weight: 110.1 kDa

UniProt: Q9D5Y1

AlphaFold: Q9D5Y1