RIN2 Protein (AA 1-903) (His tag)

Catalog No. ABIN7564990

Product Details

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Protein Type: Recombinant

Protein Characteristics: AA 1-903

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This RIN2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Rin2 Protein expressed in mammalian cells.

Sequence: MSAWTMGAQG LDKRGSFFKL IDTIASEIGE LKREMVQTDI SRENGLEPSE THSMVRHKDG GYSEDKDGKT CPRDSGYDSL SNRLSILDRL LHTHPIWLQL SLSEEEAAEV LQAQPPGIFL VRKSSKMQKK VLSLRLPCEF GAPLKEFTIK ESTYTFSLEG SGISFADLFR LIAFYCISRD VLPFTLKLPY AISTAKTESQ LEELAQLGLN FWSSSADNKP LNSPPPHRPL PSAGICPASL RQLCLINGVH SIKTRTPSEL ECSQTNGALC FINPLFLKVH SQDLSTGPKR PSTRTPNANG TERPRSPPPR PPPPAINSLH TSPGLSRTEP QTSMPETVNH SKHGNVALLG TKPTPIPPPR LKKQASFLEA ESSAKTLTAR RPSRRSEPEP ELELELEMGT AGHAGGAPPR DAPGDCTRAP PPGSESQPPP CHGARQRLSD MSLSTSSSDS LEFDRSMPLY GYEADTTSSL EDYEGESDQE TMAPPIKSKK KRNSSFVLPK LVKSQLRKMS GVFSSFMTPE KRMVRRIAEL SRDKCTYFGC LVQDYVSFLK ENKECHVSST DMLQTIRQFM TQVKNYLSQS SELDPPIESL IPEDQIDVVL EKAMHKCILK PLKGHVEAML KDFHTADGSW KQLKENLQLV RQRNPQELGV FAPTPDLMEL EKIKLKFMTM QKMYSPEKKV MLLLRVCKLI YTVMENNSGR MYGADDFLPV LTYVIAQCDM LELDTEIEYM MELLDPSLLH GEGGYYLTSA YGALSLIKNF QEEQAARLLS SEARDTLRQW HKRRTTNRTI PSVDDFQNYL RVAFQEVNSG CTGKTLLVRP YITTEDVCQL CAEKFKVEDP EEYSLFLFVD ETWQQLAEDT YPQKIKAELH SRPQPHIFHF VYKRIKSDPY GVIFQNGEDL TPS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Alternative Name: Rin2 (RIN2 Products)

Background: Ras and Rab interactor 2 (Ras interaction/interference protein 2),FUNCTION: Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP (By similarity). {ECO:0000250}.

Molecular Weight: 101.6 kDa

UniProt: Q9D684

AlphaFold: Q9D684