Interleukin enhancer-binding factor 3 (ILF3) (AA 1-898) protein (His tag)
-
- Target See all Interleukin enhancer-binding factor 3 (ILF3) Proteins
- Interleukin enhancer-binding factor 3 (ILF3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-898
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Made-to-order recombinant Ilf3 Protein expressed in mammalian cells.
- Sequence
- MRPMRIFVND DRHVMAKHSS VYPTQEELEA VQNMVSHTER ALKAVSDWID EQEKGNSELS EAENMDTPPD DESKEGAGEQ KAEHMTRTLR GVMRVGLVAK GLLLKGDLDL ELVLLCKEKP TTALLDKVAD NLAIQLTTVT EDKYEILQSV DDAAIVIKNT KEPPLSLTIH LTSPVVREEM EKVLAGETLS VNDPPDVLDR QKCLAALASL RHAKWFQARA NGLKSCVIVI RVLRDLCTRV PTWGPLRGWP LELLCEKSIG TANRPMGAGE ALRRVLECLA SGIVMPDGSG IYDPCEKEAT DAIGHLDRQQ REDITQSAQH ALRLAAFGQL HKVLGMDPLP SKMPKKPKNE NPVDYTVQIP PSTTYAITPM KRPMEEDGEE KSPSKKKKKI QKKEEKADPP QAMNALMRLN QLKPGLQYKL ISQTGPVHAP IFTMSVEVDG SNFEASGPSK KTAKLHVAVK VLQDMGLPTG AEGRDSSKGE DSAEESDGKP AIVAPPPVVE AVSNPSSVFP SDATTEQGPI LTKHGKNPVM ELNEKRRGLK YELISETGGS HDKRFVMEVE VDGQKFQGAG SNKKVAKAYA ALAALEKLFP DTPLALEANK KKRTPVPVRG GPKFAAKPHN PGFGMGGPMH NEVPPPPNIR GRGRGGNIRG RGRGRGFGGA NHGGGYMNAG AGYGSYGYSS NSATAGYSQF YSNGGHSGNA GGGGSGGGGG SSSYSSYYQG DSYNSPVPPK HAGKKPLHGG QQKASYSSGY QSHQGQQQPY NQSQYSSYGT PQGKQKGYGH GQGSYSSYSN SYNSPGGGGG SDYSYDSKFN YSGSGGRSGG NSYGSSGSSS YNTGSHGGYG TGSGGSSSYQ GKQGGYSSQS NYSSPGSSQS YSGPASSYQS SQGGYSRNTE HSMNYQYR Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
-
Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product ILF3 Protein
-
Interleukin enhancer-binding factor 3 (ILF3) (AA 1-894) protein (His tag)
custom-made ILF3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin enhancer-binding factor 3 (ILF3) (AA 1-158) protein (GST tag)ILF3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin enhancer-binding factor 3 (ILF3) (AA 1-702) protein (GST tag)ILF3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin enhancer-binding factor 3 (ILF3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ILF3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
-
- Target
- Interleukin enhancer-binding factor 3 (ILF3)
- Alternative Name
- Ilf3 (ILF3 Products)
- Background
- Interleukin enhancer-binding factor 3,FUNCTION: RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back-splicing circularization of pre-mRNAs. Within the nucleus, promotes circRNAs processing by stabilizing the regulatory elements residing in the flanking introns of the circularized exons. Plays thereby a role in the back-splicing of a subset of circRNAs. As a consequence, participates in a wide range of transcriptional and post-transcriptional processes. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs (By similarity). Upon viral infection, ILF3 accumulates in the cytoplasm and participates in the innate antiviral response. Mechanistically, ILF3 becomes phosphorylated and activated by the double-stranded RNA-activated protein kinase/PKR which releases ILF3 from cellular mature circRNAs. In turn, unbound ILF3 Molecules are able to interact with and thus inhibit viral mRNAs. {ECO:0000250|UniProtKB:Q12906, ECO:0000269|PubMed:21123651}.
- Molecular Weight
- 96.0 kDa
- UniProt
- Q9Z1X4
- AlphaFold
- Q9Z1X4
- Pathways
- M Phase
-
