BMP2 Protein (AA 289-396) (His tag)
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- Target See all BMP2 Proteins
- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 289-396
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BMP2 protein is labelled with His tag.
- Purpose
- BMP-2 (human) (rec.) (His)
- Cross-Reactivity
- Human
- Characteristics
- Human BMP-2 (aa 289-396) is fused at the C-terminus to a His-tag.
- Purity
- >95 % (SDS-PAGE)
- Sterility
- Sterile filtered
- Endotoxin Level
- <0.1EU/μg protein (LAL test, Lonza).
- Top Product
- Discover our top product BMP2 Protein
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Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) (Active) protein
BMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active
Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) proteinBMP2 Origin: Human, Dog, Mouse, Rat, Rhesus Monkey Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) protein (Fc Tag)BMP2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Bone Morphogenetic Protein 2 (BMP2) (AA 1-396) protein (GST tag)BMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 2 (BMP2) (AA 231-330) protein (GST tag)BMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) protein (GST tag)BMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 2 (BMP2) (AA 284-396) proteinBMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >92 % as determined by SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from 0.2μm-filtered solution in PBS.
- Handling Advice
- Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- Target
- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
- Alternative Name
- BMP-2 (BMP2 Products)
- Background
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BMP2, Bone Morphogenetic Protein 2
Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and regeneration. BMP-2 signals through heterodimeric complexes composed of a type I receptor (Activin RI, BMP-RIA or BMP-RIB) and a type II receptor (BMP-RII or Activin RIIB). BMP-2 induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth and bone and cartilage repair. It induces ectopic bone formation or calcification by promoting osteogenic and chondrogenic differentiation in mesenchymal cells, stem cells and vascular smooth muscle cells. It also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells and is required for cardiac contractility.
- NCBI Accession
- NP_001191
- Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
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