IL-10 Protein (AA 19-178) (His tag)
-
- Target See all IL-10 (IL10) Proteins
- IL-10 (IL10) (Interleukin 10 (IL10))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-178
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL-10 protein is labelled with His tag.
- Purpose
- IL-10 (human) (rec.) (His)
- Cross-Reactivity
- Human
- Characteristics
- Human IL-10 (aa 19-178) is fused at the N-terminus to a His-tag.
- Purity
- >95 % (SDS-PAGE)
- Sterility
- Sterile filtered
- Endotoxin Level
- <0.1EU/μg protein (LAL test, Lonza).
- Top Product
- Discover our top product IL10 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from 0.2μm-filtered solution in PBS ( pH 7.4).
- Handling Advice
- Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
- Storage
- 4 °C,-20 °C
- Storage Comment
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
-
- Target
- IL-10 (IL10) (Interleukin 10 (IL10))
- Alternative Name
- IL-10 (IL10 Products)
- Background
-
Interleukin-10, Cytokine Synthesis Inhibitory Factor, CSIF
Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
- NCBI Accession
- NP_000563
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
-