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IL-10 Protein (AA 19-178) (His tag)

IL10 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE)
Catalog No. ABIN7566175
  • Target See all IL-10 (IL10) Proteins
    IL-10 (IL10) (Interleukin 10 (IL10))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 19-178
    Origin
    • 24
    • 14
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 31
    • 22
    • 17
    • 11
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IL-10 protein is labelled with His tag.
    Purpose
    IL-10 (human) (rec.) (His)
    Cross-Reactivity
    Human
    Characteristics
    Human IL-10 (aa 19-178) is fused at the N-terminus to a His-tag.
    Purity
    >95 % (SDS-PAGE)
    Sterility
    Sterile filtered
    Endotoxin Level
    <0.1EU/μg protein (LAL test, Lonza).
    Top Product
    Discover our top product IL10 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from 0.2μm-filtered solution in PBS ( pH 7.4).
    Handling Advice
    Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
    Storage
    4 °C,-20 °C
    Storage Comment

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

  • Target
    IL-10 (IL10) (Interleukin 10 (IL10))
    Alternative Name
    IL-10 (IL10 Products)
    Background

    Interleukin-10, Cytokine Synthesis Inhibitory Factor, CSIF

    Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.

    NCBI Accession
    NP_000563
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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