K-RAS Protein (GST tag)

Catalog No. ABIN7577835

This Recombinant K-RAS protein is produced in Escherichia coli (E. coli). There is 1 publication available.

Quick Overview for K-RAS Protein (GST tag) (ABIN7577835)

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB), ELISA, SDS-PAGE (SDS)

Product Details

Purification tag / Conjugate: This K-RAS protein is labelled with GST tag.

Purpose: Recombinant Human KRAS/K-Ras 2 (G12C) Protein, N-GST

Sequence: Met1-Met188

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile water for a stock solution.

Buffer: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4 % Trehalose, 1 % Mannitol.

Storage: 4 °C,-20 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 °C for twelve months from the date of receipt.

References

Duo, Chen, Liu, Ma, Farjudian, Ho, Low, Ren, Hirst, Xie, Tang: "Discovery of novel SOS1 inhibitors using machine learning." in: RSC medicinal chemistry, Vol. 15, Issue 4, pp. 1392-1403, (2024) (PubMed).

Target Details

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Alternative Name: KRAS/K-Ras 2

Target Type: Viral Protein

Background: C-Ki-ras, RASK2, GTPase KRas, K-Ras 2, c-K-ras, KRAS, Ki-Ras, KRAS2, G12C, Gly12Cys

Molecular Weight: 48.3 kDa

UniProt: P01116-2