BMP2 Protein (AA 283-396)
Quick Overview for BMP2 Protein (AA 283-396) (ABIN7596119)
Target
See all BMP2 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 283-396
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Sequence
- MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
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Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Biological Activity Comment
- Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is ≤ 100 ng/ml.
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Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) (Active) protein
BMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active
Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) proteinBMP2 Origin: Human, Dog, Mouse, Rat, Rhesus Monkey Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) protein (Fc Tag)BMP2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Bone Morphogenetic Protein 2 (BMP2) (AA 231-330) protein (GST tag)BMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) protein (GST tag)BMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 2 (BMP2) (AA 1-396) protein (GST tag)BMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 2 (BMP2) (AA 284-396) proteinBMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >92 % as determined by SDS-PAGE.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
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Alternative Name
- BMP-2
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Background
- BMP-2, also known as Bone morphogenetic protein 2, is multi-functional growth factor that belongs to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility. Recombinant human BMP2 was expressed in E. coli and purified by conventional chromatography techniques.
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Molecular Weight
- 13 kDa (115aa)
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NCBI Accession
- NP_001191
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
Target
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