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CD200 Protein (CD200) (AA 31-232) (hIgG-His-tag)

Recombinant CD200 protein expressed in Baculovirus infected Insect Cells.
Catalog No. ABIN7596333

Quick Overview for CD200 Protein (CD200) (AA 31-232) (hIgG-His-tag) (ABIN7596333)

Target

See all CD200 Proteins
CD200

Protein Type

Recombinant

Origin

  • 23
  • 9
  • 2
  • 1
Mouse

Source

  • 15
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Baculovirus infected Insect Cells

Application

SDS-PAGE (SDS)

Purity

> 95% by SDS-PAGE
  • Protein Characteristics

    AA 31-232

    Purification tag / Conjugate

    This CD200 protein is labelled with hIgG-His-tag.

    Sequence

    QVEVVTQDER KALHTTASLR CSLKTSQEPL IVTWQKKKAV SPENMVTYSK THGVVIQPAY KDRINVTELG LWNSSITFWN TTLEDEGCYM CLFNTFGSQK VSGTACLTLY VQPIVHLHYN YFEDHLNITC SATARPAPAI SWKGTGTGIE NSTESHFHSN GTTSVTSILR VKDPKTQVGK EVICQVLYLG NVIDYKQSLD KG

    Endotoxin Level

    < 1 EU per 1ug of protein (determined by LAL method)
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target

    CD200

    Alternative Name

    CD200

    Background

    CD200, also known as OX-2 membrane glycoprotein isoform 1, is one of the immunoglobulin superfamily. It plays an important role in anti-tumor immunity through interaction with its receptor, and overexpression of this protein effects on malignancies as well as on cancer stem cells. In T cells, this protein functions as a co-stimulatory effect that is independent of the CD28 pathway. It also plays an important role on myeloid cell regulation that is suggested by restricted expression of its receptor. Studies of this protein in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Recombinant mouse CD200, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

    Molecular Weight

    49.5 kDa (441aa)

    NCBI Accession

    NP_034948
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