CCR2 Protein (DYKDDDDK Tag,Strep Tag)
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- Target See all CCR2 Proteins
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR2 protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- ELISA, Immunogen (Imm), Surface Plasmon Resonance (SPR), Cryogenic electron microscopy (cryo-EM), Phage Display (PhD)
- Purpose
- Human CCR2-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product CCR2 Protein
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Chemokine (C-C Motif) Receptor 2 (CCR2) protein
CCR2 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-374) protein (His tag)custom-made CCR2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-373) protein (His tag)custom-made CCR2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-360) (Active) protein-VLPCCR2 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, SPR, Func Active
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-360) (Active) protein-VLP (Biotin)CCR2 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, SPR, Func Active
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-55) protein (Fc Tag)CCR2 Origin: Mouse Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-42) protein (Fc Tag)CCR2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-42) protein (GST tag)CCR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-42) protein (mFc Tag)CCR2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Alternative Name
- CCR2 (CCR2 Products)
- Background
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CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
The protein is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. - Molecular Weight
- The human full length CCR2-Strep protein has a MW of 41.9 kDa
- UniProt
- P41597
- Pathways
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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