STING1 protein (DYKDDDDK Tag,Strep Tag)
Origin: Human
Host: HEK-293 Cells
Synthetic Nanodisc
cryo-EM, ELISA, Imm, PhD, SPR
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- Target
- STING1
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- DYKDDDDK Tag,Strep Tag
- Application
- Cryogenic electron microscopy (cryo-EM), ELISA, Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human STING1-Strep full length protein-synthetic nanodisc
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STING1 protein
Origin: Human Host: Mammalian Cells Synthetic Nanodisc
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- STING1
- Background
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ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173
A five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. - Molecular Weight
- The human full length STING1-Strep protein has a MW of 42.2 kDa
- UniProt
- Q86WV6
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