CX3CR1 Protein (DYKDDDDK Tag,Strep Tag)
Quick Overview for CX3CR1 Protein (DYKDDDDK Tag,Strep Tag) (ABIN7596594)
Target
See all CX3CR1 ProteinsProtein Type
Origin
Source
Application
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Purification tag / Conjugate
- This CX3CR1 protein is labelled with DYKDDDDK Tag,Strep Tag.
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Purpose
- Human CX3CR1-Strep full length protein-synthetic nanodisc
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Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
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Alternative Name
- CX3CR1
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Background
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CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. -
Molecular Weight
- The human full length CX3CR1-Strep protein has a MW of 40.4 kDa
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UniProt
- P49238
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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