Calcitonin Receptor Protein (CALCR) (DYKDDDDK Tag,Strep Tag)
CALCR
Origin: Human
Host: HEK-293 Cells
Synthetic Nanodisc
Imm, ELISA, cryo-EM, PhD, SPR
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- Target See all Calcitonin Receptor (CALCR) Proteins
- Calcitonin Receptor (CALCR)
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Calcitonin Receptor protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human CALCR-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product CALCR Protein
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Calcitonin Receptor (CALCR) (AA 1-474) protein (GST tag)
CALCR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Calcitonin Receptor (CALCR)
- Alternative Name
- CALCR (CALCR Products)
- Background
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CRT, CT-R, CTR, CTR1
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] - Molecular Weight
- The human full length CALCR-Strep protein has a MW of 55.3kDa
- UniProt
- P30988
- Pathways
- cAMP Metabolic Process
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