CCKAR Protein (DYKDDDDK Tag,Strep Tag)
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- Target See all CCKAR Proteins
- CCKAR (Cholecystokinin A Receptor (CCKAR))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCKAR protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human CCKAR-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product CCKAR Protein
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCKAR (Cholecystokinin A Receptor (CCKAR))
- Alternative Name
- CCKAR (CCKAR Products)
- Background
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CCK-A, CCK1-R, CCK1R, CCKRA
This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length CCKAR-Strep protein has a MW of 47.8 kDa
- UniProt
- P32238
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour
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