CCRL2 Protein (DYKDDDDK Tag,Strep Tag)
Quick Overview for CCRL2 Protein (DYKDDDDK Tag,Strep Tag) (ABIN7596697)
Target
See all CCRL2 ProteinsProtein Type
Origin
Source
Application
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Purification tag / Conjugate
- This CCRL2 protein is labelled with DYKDDDDK Tag,Strep Tag.
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Purpose
- Human CCRL2-Strep full length protein-synthetic nanodisc
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Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))
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Alternative Name
- CCRL2
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Background
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ACKR5, CKRX, CRAM, CRAM-A, CRAM-B, HCR
This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008] -
Molecular Weight
- The human full length CCRL2-Strep protein has a MW of 39.5 kDa
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UniProt
- O00421
Target
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