HRH4 Protein (DYKDDDDK Tag,Strep Tag)
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- Target See all HRH4 Proteins
- HRH4 (Histamine Receptor H4 (HRH4))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HRH4 protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human HRH4-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product HRH4 Protein
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- HRH4 (Histamine Receptor H4 (HRH4))
- Alternative Name
- HRH4 (HRH4 Products)
- Background
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AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] - Molecular Weight
- The human full length HRH4-Strep protein has a MW of 44.5 kDa
- UniProt
- Q9H3N8
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