NMBR Protein (DYKDDDDK Tag,Strep Tag)
Quick Overview for NMBR Protein (DYKDDDDK Tag,Strep Tag) (ABIN7596838)
Target
Protein Type
Origin
Source
Application
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Purification tag / Conjugate
- This NMBR protein is labelled with DYKDDDDK Tag,Strep Tag.
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Purpose
- Human NMBR-Strep full length protein-synthetic nanodisc
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Neuromedin B Receptor (NMBR) (AA 1-390) protein (His tag)
custom-made NMBR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Neuromedin B Receptor (NMBR) (AA 1-390) protein (His tag)custom-made NMBR Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- NMBR (Neuromedin B Receptor (NMBR))
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Alternative Name
- NMBR
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Background
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BB1, BB1R, BRS1, NMB-R
This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] -
Molecular Weight
- The human full length NMBR-Strep protein has a MW of 43.4 kDa
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UniProt
- P28336
Target
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