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OPRL1 Protein (DYKDDDDK Tag,Strep Tag)

OPRL1 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc ELISA, cryo-EM, Imm, PhD, SPR
Catalog No. ABIN7596861
  • Target See all OPRL1 Proteins
    OPRL1 (Opiate Receptor-Like 1 (OPRL1))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 4
    • 2
    Human
    Source
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This OPRL1 protein is labelled with DYKDDDDK Tag,Strep Tag.
    Application
    ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
    Purpose
    Human OPRX-Strep full length protein-synthetic nanodisc
    Top Product
    Discover our top product OPRL1 Protein
  • Comment

    Advantages:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    • Mammalian cell expression system ensures post- translational modifications

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    OPRL1 (Opiate Receptor-Like 1 (OPRL1))
    Alternative Name
    OPRX (OPRL1 Products)
    Background
    KOR-3, KOR3, NOCIR, NOP, NOPr, OOR, OPRL, ORL1, PNOCR
    The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
    Molecular Weight
    The human full length OPRX-Strep protein has a MW of 40.7 kDa
    UniProt
    P41146
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