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CYBB Protein (DYKDDDDK Tag,Strep Tag)

CYBB Origin: Human Host: HEK-293 Cells Synthetic Nanodisc Imm, ELISA, cryo-EM, PhD, SPR
Catalog No. ABIN7596998
  • Target See all CYBB Proteins
    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
    Protein Type
    Synthetic Nanodisc
    Origin
    Human
    Source
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CYBB protein is labelled with DYKDDDDK Tag,Strep Tag.
    Application
    Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
    Purpose
    Human CY24B-Strep full length protein-synthetic nanodisc
    Top Product
    Discover our top product CYBB Protein
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  • Comment

    Advantages:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    • Mammalian cell expression system ensures post- translational modifications

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
    Alternative Name
    CY24B (CYBB Products)
    Background
    AMCBX2, CGD, CGDX, GP91-1, GP91-PHOX, GP91PHOX, IMD34, NOX2, p91-PHOX
    Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
    Molecular Weight
    The human full length CY24B-Strep protein has a MW of 65.3 kDa
    UniProt
    P04839
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