Bestrophin 4 Protein (BEST4) (DYKDDDDK Tag,Strep Tag)
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- Target See all Bestrophin 4 (BEST4) Proteins
- Bestrophin 4 (BEST4)
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Bestrophin 4 protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- ELISA, Immunogen (Imm), Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human BEST4-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product BEST4 Protein
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Bestrophin 4 (BEST4)
- Alternative Name
- BEST4 (BEST4 Products)
- Background
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VMD2L2
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length BEST4-Strep protein has a MW of 53.5 kDa
- UniProt
- Q8NFU0
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