GABRE Protein (DYKDDDDK Tag,Strep Tag)
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- Target See all GABRE Proteins
- GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GABRE protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human GBRE-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product GABRE Protein
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- Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))
- Alternative Name
- GBRE (GABRE Products)
- Background
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N/A
The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008] - Molecular Weight
- The human full length GBRE-Strep protein has a MW of 58 kDa
- UniProt
- P78334
- Pathways
- Synaptic Membrane
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