CCR3 Protein
Quick Overview for CCR3 Protein (ABIN7597219)
Target
See all CCR3 ProteinsProtein Type
Origin
Source
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Purpose
- Human CCR3 full length protein-MNP
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Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 1-359) protein (His tag)
custom-made CCR3 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 1-355) protein (His tag)custom-made CCR3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-C Motif) Receptor 3 (CCR3) proteinCCR3 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 1-355) protein (GST tag)CCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 1-34) protein (Fc Tag)CCR3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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Alternative Name
- CCR3
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Background
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CC-CKR-3, C C CKR3, CD193, CKR 3, CKR3, CMKBR3
The protein is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. -
Molecular Weight
- The human full length CCR3 protein has a MW of 41.0 kDa
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UniProt
- P51677
Target
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