CCL7 Protein (AA 24-99) (Fc Tag)

Catalog No. ABIN7597415

Product Details

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Protein Type: Recombinant

Protein Characteristics: AA 24-99

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CCL7 protein is labelled with Fc Tag.

Purpose: Recombinant human CCL7 Protein with C-terminal human Fc tag

Sequence: CCL7(Gln24-Leu99) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Alternative Name: CCL7 (CCL7 Products)

Background: FIC, MARC, MCP3, NC28, MCP-3, SCYA6, SCYA7
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 35.1 kDa after removal of the signal peptide. The apparent molecular mass of CCL7-hFc is 35-55 kDa due to glycosylation.

UniProt: P80098