OR1A1 Protein (AA 1-25) (Fc Tag)

Catalog No. ABIN7597430

Product Details

Target: OR1A1 (Olfactory Receptor, Family 1, Subfamily A, Member 1 (OR1A1))

Protein Type: Recombinant

Protein Characteristics: AA 1-25

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This OR1A1 protein is labelled with Fc Tag.

Purpose: Recombinant human OR1A1 Protein with C-terminal human Fc tag

Sequence: OR1A1(Met1-Asp25) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: OR1A1 (Olfactory Receptor, Family 1, Subfamily A, Member 1 (OR1A1))

Alternative Name: OR1A1 (OR1A1 Products)

Background: OR17-7
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 29.0 kDa after removal of the signal peptide. The apparent molecular mass of OR1A1-hFc is 35-55 kDa due to glycosylation.

UniProt: Q9P1Q5