IL1F9 Protein (AA 13-164)

Catalog No. ABIN7668991

This Recombinant IL1F9 protein is produced in Escherichia coli (E. coli).

Quick Overview for IL1F9 Protein (AA 13-164) (ABIN7668991)

Target: IL1F9 (Interleukin 1 Family Member 9 (IL1F9))

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: > 95 %

Product Details

Protein Characteristics: AA 13-164

Purpose: Recombinant Mouse Interleukin-36 gamma/IL-36 gamma/IL-1F9

Sequence: Gly13-Ser164

Purification: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2μm filtered solution of 20 mM Histidine-HCl, 10 % Trehalose, 0.05 % Tween 80, pH 5.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: IL1F9 (Interleukin 1 Family Member 9 (IL1F9))

Alternative Name: IL-36 gamma,IL-1F9

Background: Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.,Il1f,IL-1-related protein,Interleukin-1 homolog,IL-1F,IL-1H,IL-1RP,IL-1 epsilon,IL-1F9,IL-1H1,IL-1-related protein 2,IL-1RP2,Interleukin-1 homolog 1,Interleukin-36 gamma,Il1f9,Il36g,IL-17E

Molecular Weight:

calculated_mw: 17.3 kDa

observed_mw: 17 kDa

UniProt: Q8R460