PNOC Protein (His tag)

Catalog No. ABIN7669456

This Recombinant PNOC protein is produced in Escherichia coli (E. coli).

Quick Overview for PNOC Protein (His tag) (ABIN7669456)

Target: PNOC (Prepronociceptin (PNOC))

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 %

Product Details

Purification tag / Conjugate: This PNOC protein is labelled with His tag.

Purpose: Recombinant Human OFQ/N protein (His tag)

Sequence: Ser 20-Val 176

Purification: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 10 EU/mg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: PNOC (Prepronociceptin (PNOC))

Alternative Name: PNOC,OFQ

Background: This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include nociceptin, nocistatin, and orphanin FQ2 (OFQ2). Nociceptin, also known as orphanin FQ, is a 17-amino acid neuropeptide that binds to the nociceptin receptor to induce increased pain sensitivity, and may additionally regulate body temperature, learning and memory, and hunger. Another product of the encoded preproprotein, nocistatin, may inhibit the effects of nociceptin.,PNOC,N/OFQ,NOP,OFQ,PPNOC,Prepronociceptin,ppN/OFQ

Molecular Weight:

calculated_mw: 17.2 kDa

observed_mw: 23 kDa

UniProt: Q13519